Mechlorethamine FDA Link

A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.

Also Known As:

Nitrogen Mustard; Chlormethine; Mustargen; Mustine; Bis(2-chloroethyl)methylamine; Caryolysine; Cloramin; Embichin; Mechlorethamine Hydrochloride; Mechlorethamine Hydrochloride N-Oxide; Mechlorethamine N-Oxide; Methylchlorethamine; Mitomen; NSC-10107; NSC-762; Nitrogranulogen; Nitromin; Hydrochloride N-Oxide, Mechlorethamine; Hydrochloride, Mechlorethamine; Mechlorethamine Hydrochloride N Oxide; Mechlorethamine N Oxide; N-Oxide, Mechlorethamine Hydrochloride; N-Oxide, Nitrogen Mustard; NSC 10107; NSC 762; NSC10107; NSC762; Nitrogen Mustard N Oxide; Chlorethazine; Mechlorethamine Oxide; Nitrogen Mustard N-Oxide; Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl-

Pharmalogical Action Categories:

Alkylating Agents
Antineoplastic Agents, Alkylating
Chemical Warfare Agents
Irritants

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Halogenated Hydrocarbons: 42
    - Mustard Compounds: 3
      - Nitrogen Mustard Compounds: 2
        Mechlorethamine: 1690

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Disease

Drug/Important Bio-Agent (IBA)